Supernatural and horror literature

H​‌‍‍‍‌‍‍‌‍‌‌‍‍‍‌‍‌‌‌‍​ow did the traditional, scientific study of biology influe​‌‍‍‍‌‍‍‌‍‌‌‍‍‍‌‍‌‌‌‍​nce the subgenre of horror literature known as bio-horror​‌‍‍‍‌‍‍‌‍‌‌‍‍‍‌‍‌‌‌‍​?