The purpose of this review article is to search different data bases for studies on children conceived naturally and through different ART especially ICSI and Frozen embryo transfer to see if there is any association with there procedures and cancer in children specifically leukemia and other hematological malignancies.
Introduction: containing definitions and epidemiology of ART and pediatric cancer world wide and if there is in middle east specifically Saudi Arabia. It also should include the aim
Body: divided into
-how the technique of the ART is done and specific details regarding the procedure
-materials and methodologies which data bases were searched what key words were used
-results from the search and if there is any link between ART-ICSI -Frozen embryo transfer and hematological cancer in children
-discussion regarding what are the genetic changes that happen due to these procedures that might cause the hematological cancer
-strength and limitations in the field
conclusion:
Reference:
